Step 1 Basic Science Review by Aaron Caughey

By Aaron Caughey

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Cereus E. B. cereus and C. perfringens 24 2. If SS’s stool culture showed comma- or S-shaped gram-negative rods, which of the listed agents is the most likely etiology of her diarrhea? A. Giardia lamblia B. Salmonella typhi C. Bacillus cereus D. Campylobacter jejuni E. qxd 11/13/08 CASE 1-9 2:17 PM Page 25 Pseudomonas Aeruginosa HPI: PA is an 18-year-old female with cystic fibrosis who presents to the emergency department with 2 days of worsening shortness of breath and cough. Her cough is productive of greenish sputum and she also complains of a low-grade fever.

Transmission and Epidemiology N. meningitides organisms are transmitted from person to person by airborne respiratory droplets, after which time they can temporarily colonize the nasopharynx in the exposed individual (although carriers are usually asymptomatic). The organism then enters the bloodstream from the nasopharynx and is disseminated either widely or just to the meninges. Approximately 5% of the population are chronic carriers of N. meningitides and serve as a source of infection to others.

Serious infections often require combination therapy among these classes of antibiotics. TABLE 1-4 Antibiotic Classes THUMBNAIL: P. aeruginosa Pneumonia Organism P. aeruginosa Type of organism Oxidase-positive, aerobic Gram-negative rod Diseases caused Respiratory tract infections, especially in patients with cystic fibrosis and chronic lung disease, UTIs, external otitis and malignant external otitis, bacteremia, ecthyma gangrenosum, skin and soft tissue infections, bone and joint infections, eye infections, and necrotizing enterocolitis in young infants and neutropenic patients Epidemiology P.

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